New Visible Spectrophotometric Method for the Determination of Cefixime Trihydrate in Pharmaceutical Formulations
نویسنده
چکیده
A simple, sensitive and economical spectrophotometric method was developed for the determination of cefixime trihydrate in pharmaceutical formulations. This method is based on the formation of pink colored chromogen complex by the reaction of drug with ferric chloride and 2, 2 bipyridyl, which absorbs maximally at 520 nm. Beer’s law is obeyed at a concentration range of 110 mcg/ml for method. This method has been successfully applied for the assay of the drug in pharmaceutical formulations.
منابع مشابه
Spectrophotometric Determination of Cefixime Trihydrate in Pharmaceutical Formulations Based on Ion-Pair Reaction with Bromophenol Blue
Cefixime trihydrate is a broad spectrum cephalosporin antibiotic, effective against gram-positive and gram-negative bacterial infections. Simple and rapid method has been developed for the determination of cefixime trihydrate in bulk and pharmaceutical formulations. This method was based on the formation of bluish-green ion-pair complex of cefixime trihydrate with bromophenol blue in dimethyl s...
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